Strategic Insights

GLP-1 Spending and the Case for Comprehensive Cardiometabolic Care

Sword Health Innovation Team

Footnotes

  1. 1

    Marsh. 2026 National Survey of Employer-Sponsored Health Plans, Preliminary Results. September 2, 2026.

  2. 2

    Mercer. Survey on Health and Benefit Strategies for 2027. June 11, 2026.

  3. 3

    Rodriguez PJ, Zhang V, Gratzl S, et al. Discontinuation and reinitiation of dual-labeled GLP-1 receptor agonists among US adults with overweight or obesity. JAMA Network Open. 2025;8(1).

  4. 4

    Sword. GLP-1 Wraparound Pilot. Internal program data, March–June 2026. Unpublished findings. Patient Global Impression of Change assessment, n=90.

  5. 5

    Wilding JPH, Batterham RL, Davies M, et al. Weight regain and cardiometabolic effects after withdrawal of semaglutide: the STEP 1 trial extension. Diabetes, Obesity and Metabolism. 2022;24(8):1553–1564.

  6. 6

    Karakasis P, Patoulias D, Fragakis N, Mantzoros CS. Effect of glucagon-like peptide-1 receptor agonists and co-agonists on body composition: systematic review and network meta-analysis. Metabolism. 2025;164:156113.

  7. 7

    World Health Organization. WHO Issues Global Guideline on the Use of GLP-1 Medicines in Treating Obesity. December 1, 2025.

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